NU641 Advanced Clinical Pharmacology
Week 1 Discussion
DQ1 Drug Categories
Initial Post
Your initial post should contain two to three well-developed paragraphs using APA formatting, integrating two evidence-based resources to include clinical practice guidelines, as well as the course textbook.
In your initial post, please select two classifications of drugs from the following list and explain the factors that may influence the pharmacokinetics and pharmacodynamics processes of these agents.
List of Drug Categories
Selective Serotonin Inhibitors
Fluoroquinolones
Beta-Adrenergic Antagonists
Antilipidemics
Corticosteriods
ACE Inhibitors
Reply Posts
Respond to a minimum of two peers on two separate days. Your responses should be in a well-developed paragraph (300-350 words) to each peer. Integrating an evidence-based resource that is different than the one you used for the initial post.
Your responses to each peer’s chosen drug categories should include one evidence-based article from the Regis College Library that connects culture, genomics, pharmacogenomics, or a particular age group (infant or pregnancy, for example.)
Respectfully agree and disagree with your peers’ responses and explain your reasoning by including your rationales in your explanation.
Please refer to the Grading Rubric for details on how this activity will be graded.
The described expectations meet the passing level of 80%. Students are directed to review the Discussion Grading Rubric for criteria, which exceed expectations.
DQ2 Prescription Writing
Overview
A prescription is an order from a physician to a pharmacist that indicates the medication that a patient is to take. If the prescription is poorly written, this can lead to medication error. Here are some statistics:
Medication errors occur in approximately 1 in every 5 doses given in hospitals.
One error occurs per patient per day.
Approximately 1.3 million injuries and 7,000 deaths occur each year in the U.S. from medication-related errors.
Drug-related morbidity and mortality are estimated to cost $177 billion in the U.S.
These are estimates from various sources and studies and provide shocking evidence about prescriptions. It is no wonder why malpractice insurance is so expensive?
Initial Post
Please review your course materials and research to evaluate the proper ways to write prescriptions.
For your initial post, share one piece of knowledge that you have found along with the resource information. Practice writing a prescription and submit that along with your post for your peers to evaluate.
Reply Posts
Respond to a minimum of two peers on two separate days. Your responses should be in a well-developed paragraph (300-350 words) to each peer. Integrating an evidence-based resource that is different than the one you used for the initial post.
Respectfully agree and disagree with your peers’ responses and explain your reasoning by including your rationales in your explanation.
Please refer to the Grading Rubric for details on how this activity will be graded.
The described expectations meet the passing level of 80%. Students are directed to review the Discussion Grading Rubric for criteria, which exceed expectations.
NU641 Advanced Clinical Pharmacology
Week 3 Discussion
Heart Failure
Initial Post
Answer the following questions in three well-developed paragraphs (450–500 words) using APA formatting, integrating two evidence-based resources to include clinical practice guidelines as well as the course textbook.
Topic: Heart Failure
ML is a retired registered nurse (RN) who has been given the diagnosis of Stage A heart failure. She knows from her RN education that she will definitely be placed on digoxin as a therapy. She remembers something about halos as something to be attuned to.
Explain the pathophysiology of Stage A heart failure.
What is the rational drug choice for treatment of this individual?
Address the patient’s concern about halos should digoxin be prescribed.
Are there gender considerations related to medication treatment in this scenario? If so, what are they? For example, do men and women differ in their side effect profile and/or complications (for instance, from digoxin)?
Discuss monitoring of the pharmacological agent(s) selected.
Reply Posts
Respond to a minimum of two peers on two separate days. Your responses should be in a well-developed paragraph (300-350 words) to each peer. Integrating an evidence-based resource that is different than the one you used for the initial post.
Respectfully agree and disagree with your peers’ responses and explain your reasoning by including your rationales in your explanation.
Please refer to the Grading Rubric for details on how this activity will be graded.
The described expectations meet the passing level of 80%. Students are directed to review the Discussion Grading Rubric for criteria, which exceed expectations.
NU641 Advanced Clinical Pharmacology
Week 4 Discussion
Gastrointestinal Case Study
Initial Post
Overview
Gastrointestinal Case Study
CF is a 48-year-old man who presents for evaluation of heartburn. He denies current tobacco use but has a history of one ppd for 15 years. He consumes a glass of wine nightly, more on the weekends. He has a sedentary job.
He reports a burning feeling in his chest after eating. It is worse when he eats spicy foods or tomato sauce. He is sometimes awakened at night with these symptoms. He has tried over-the-counter antacids and histamine H2 receptor antagonists (H2RAs) with partial relief. He is on no regular medications. His examination today is normal. An upper gastrointestinal (GI) X-ray series reveals gastroesophageal reflux.
What lifestyle modifications do you recommend for CF?
Describe a rational drug choice for this patient. Be specific regarding what factors you would consider. Include pharmacokinetic and dynamic considerations for the pharmacological choices made. Also consider interactions and side effects.
What counseling points about this medication do you give CF?
ReplyPosts
Please refer to the Grading Rubric for details on how this activity will be graded.
Respond to a minimum of two peers on two separate days. Your responses should be in a well-developed paragraph (300-350 words) to each peer. Integrating an evidence-based resource that is different than the one you used for the initial post.
Respectfully agree and disagree with your peers’ responses and explain your reasoning by Including your rationales in your explanation.
The described expectations meet the passing level of 80%. Students are directed to review the Discussion Grading Rubric for criteria, which exceed expectations.
NU641 Advanced Clinical Pharmacology
Week 5 Discussion
Pain Management Case Study
Initial Post
Answer the following questions in three well-developed paragraphs (450-500 words) using APA formatting, integrating two evidence-based resources to include clinical practice guidelines as well as the course textbook. Pain Management Case Study
As an Advanced Nurse Practitioner (ANP), you are working in an urgent care setting. TC comes to the clinic with a work-related injury to the right shoulder. The patient rates the pain 8 on a scale of 0–10. The patient is unable to perform any ROM to the shoulder. There is no neck pain.
What pieces of the holistic assessment are missing from this scenario?
As a healthcare provider, what else do you need to understand about this patient related to pain management?
Describe the process of rational drug choice for this case study. In your process, discuss your thought processing of anti-inflammatory agents, topical agents, and narcotics.
Include in your response the teaching you would provide to TC.
What is meant by the DEA Drug Classification Schedule? Explain each category/classification.
Reply Posts
Please refer to the Grading Rubric for details on how this activity will be graded.
Reply to at least two of your classmates on two separate days with a well-developed paragraph (300–350 words to each peer), integrating an evidence-based resource that is different than the one used for the initial post.
Respectfully agree and disagree with your peers’ responses and explain your reasoning by including your rationales in your explanation.
The described expectations meet the passing level of 80%. Students are directed to review the Discussion Grading Rubric for criteria which exceed expectations.
NU641 Advanced Clinical Pharmacology
Week 6 Discussion
Infection Case Study
Initial Post
Answer the following questions in three well-developed paragraphs (450–500 words) using APA formatting, integrating two evidence-based resources to include clinical practice guidelines as well as the course textbook.
RR is 48-year-old Hispanic woman who comes to see you at the V. A. homeless clinic. The major complaint is a six-day history of worsening cough, productive of green sputum. There have been fever and chills with complaints of pain in the right mid-back with deep breathing or coughing. Further history reveals a history of tobacco use of one pack of cigarettes a day for 30 years. There is an incontainent health history as a result of Post Traumatic Stress Disorder (PTSD) and homelessness. On examination, the skin is warm and clammy, pale; RR appears to not feel well; the temperature is 100.5° F; respiratory rate is 24 breaths per minute; pulse is 98 beats per minute; blood pressure is 120/75 mm Hg; and saturation of oxygen is 96 percent on room air by pulse oximetry.
Auscultation of the lungs reveals rales in the right lower-posterior lung field. The remainder of the examination is within normal limits.
What organism(s) do you most suspect and why?
What antibiotic would you recommend to treat RR with and why?
What is the mechanism of action of this antibiotic? Provide rationale
Do you have any counseling points for RR?
Reply Posts
Please refer to the Grading Rubric for details on how this activity will be graded.
Response to at least two of your classmates on two separate days, in a well-developed paragraph (300–350 words) to each peer integrating an evidence-based resource that is different than the one you used for the initial post.
Respectfully agree and disagree with your peers’ responses and explain your reasoning by including your rationales in your explanation.
The described expectations meet the passing level of 80%. Students are directed to review the Discussion Grading Rubric for criteria which exceed expectations.
NU641 Advanced Clinical Pharmacology
Week 9 Discussion
Neurology
Initial Post
Your initial post should contain two to three well-developed paragraphs (450–500 words) using APA formatting, integrating two evidence-based resources to include clinical practice guidelines as well as the course textbook. (Do not use lay press Internet sites).
Include the following in your initial post:
Explanation of the pathophysiology of the diagnosis.
Description of the drug category: Overview of use/action.
Analysis of the specific agents:
Pharmacokinetics/pharmacotherapeutics, adverse drug reactions, interactions, monitoring, patient education
Please choose two diagnoses from the following list:
Migraine
Seizure Disorder
Alzheimer’s Disease
Bell’s Palsy
Insomnia
For each of the two diagnoses you choose, select two drug categories used for treatment.
For each of the two drug categories, choose two specific pharmacological agents.
Reply Posts
Choose two peer posts that have chosen different pharmacological agents. Reply in a well-developed paragraph (300-350 words) to each peer, integrating an evidence-based resource that is different than the one you used for the initial post.
Respectfully agree and disagree with your peers’ responses and explain your reasoning by including your rationales in your explanation.
Please refer to the Grading Rubric for details on how this activity will be graded.
The described expectations meet the passing level of 80%. Students are directed to review the Discussion Grading Rubric for criteria, which exceed expectations.
NU641 Advanced Clinical Pharmacology
Week 11 Discussion
Dermatology Case Study
Initial Post
Describe the rational drug choice, pharmacokinetics/dynamics, interactions, side effects, monitoring, and patient education for one of the following:
Eczema
Psoriasis
Allergic dermatitis
Fungal infection (feet, groin, vagina, ringworm)
In your initial post, include lifespan information (for instance, does treatment differ in a child versus an older adult versus a man versus a female). Include a description of the categories of topical steroids with selection rationale to include cream versus lotion, and so on.
You can include tables in addition to narrative. Integrate two evidence-based articles no older than three years in addition to the course textbook.
Reply Posts
Reply to at least two of your classmates, in a well-developed paragraph (300–350 words) to each peer integrating an evidence-based resource that is different than the one you used for the initial post.
Respectfully agree and disagree with your peers’ responses and explain your reasoning by including your rationales in your explanation.
Please refer to the Grading Rubric for details on how this activity will be graded.
The described expectations meet the passing level of 80%. Students are directed to review the Discussion Grading Rubric for criteria which exceed expectations
NU641 Advanced Clinical Pharmacology
Week 12 Discussion
Bacterial Vaginosis
Initial Post
Your initial post should contain two to three well-developed paragraphs using APA formatting, integrating two evidence-based resources to include clinical practice guidelines as well as the course textbook.
Read the scenario and answer the following questions:
R.S. is a 32-year-old Caucasian woman who seeks treatment for a vaginal discharge that she has had for the past month. She is sexually active and has had the same partner for the past 6 months. She reports noticing an odor, especially after sexual intercourse. Her history reveals that she has been using a commercial douche on a bi-weekly basis during the past year for hygienic purposes in an attempt to prevent vaginal infections. She denies any other associated symptoms.
The physical examination reveals a white vaginal discharge. Microscopic examination of the vaginal discharge shows clue cells, and the pH is 5.5.
Diagnosis: Bacterial Vaginosis
List specific goals of treatment for this patient.
What drug therapy would you prescribe? Why?
What are the parameters for monitoring the success of the therapy?
Discuss specific patient education based on the prescribed therapy.
List one or two adverse reactions for the selected agent that would cause you to change therapy.
What would be the choice for second-line therapy? Provide rationale
What OTC or alternative medications would be appropriate for this patient?
What dietary or lifestyle changes should be recommended?
Describe one or two drug–drug or drug–food interaction for the selected agent.
Reply Posts
Your response should be in a well-developed paragraph (300–350 words) integrating an evidence-based resource that is different than the one you used for the initial post.
Respectfully agree and disagree with your peers’ responses and explain your reasoning by including your rationales in your explanation.
Please refer to the Grading Rubric for details on how this activity will be graded.
The described expectations meet the passing level of 80%. Students are directed to review the Discussion Grading Rubric for criteria which exceed expectations.
NU641 Advanced Clinical Pharmacology
Week 13 Discussion
Ophthalmic Disorders
Initial Post
Your individual post should contain of three well-developed paragraphs (450–500 words) using APA formatting, integrating two evidence-based resources to include clinical practice guidelines as well as the course textbook.
Read the scenario and answer the following questions:
Ophthalmic Disorders
V.S., age 12 Hispanic male, presents with a feeling that there is sand in his eye. He had a cold a week ago and woke up this morning with his left eye crusted with yellowish drainage. On physical examination, he has injected conjunctiva on the left side, no adenopathy, and no vision changes. His vision is 20/20. Fluorescein staining reveals no abrasion. He is allergic to sulfa.
Diagnosis: Conjunctivitis
List specific goals of treatment for V.S.
What drug therapy would you prescribe? Why?
What are the parameters for monitoring the success of the therapy?
Discuss the education you would give to the parents regarding drug therapy.
List one or two adverse reactions for the selected agent that would cause you to change therapy.
What would be the choice for second-line therapy?
What over-the-counter or alternative medications would be appropriate for V.S.?
What dietary and lifestyle changes should be recommended for V.S.?
Describe one or two drug–drug or drug–food interactions for the selected agent.
Reply Posts
Reply to at least two of your classmates, in a well-developed paragraph (300–350 words) to each peer integrating an evidence-based resource that is different than the one you used for the initial post.
Respectfully agree and disagree with your peers’ responses and explain your reasoning by including your rationales in your explanation.
Please refer to the Grading Rubric for details on how this activity will be graded.
The described expectations meet the passing level of 80%. Students are directed to review the Discussion Grading Rubric for criteria which exceed expectations.
